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Objetives

General objective

The project aims to develop an innovative three-dimensional model based on patient-derived cells for amyotrophic lateral sclerosis (ALS), using stem cells obtained from urine. This model will enable advances in understanding this rare, progressive disease, improve knowledge of its pathophysiology, and facilitate the development of more precise and effective therapies. Led by a cross-border consortium, the project also seeks to strengthen research, innovation, and technology transfer capabilities in the region, fostering significant improvements in the quality of research and available treatments for patients.

Objetives

Specific objectives

01

Creation of an innovative 3D model to advance ALS research

Develop a three-dimensional model based on cells derived from amyotrophic lateral sclerosis (ALS) patients, using stem cells obtained from urine. This model will enable a better understanding of the disease and facilitate the testing of new therapies that could improve patients’ quality of life.
02

Strengthening collaboration between Spain and Portugal

Foster a cross-border network connecting researchers and medical services in the regions of Castilla y León and Central Portugal. This joint effort will ensure better access to patients and strengthen the exchange of knowledge and technologies among leading institutions.
03

Application of advanced technologies to study ALS

Utilise innovative techniques to analyse cells from the 3D model, focusing on their metabolic and mitochondrial functions. This approach will help uncover new insights into the disease and pave the way for more effective and personalised treatments.
04

Raising awareness about ALS

Translate the project’s findings into language accessible to everyone through dissemination and communication activities. The goal is to increase awareness of amyotrophic lateral sclerosis, its impact on patients, and the potential solutions offered by this project.
Cross 3D tool 4 ALS
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